The Duffy Study Room holds approximately 25,000 prints, 8,000 drawings and watercolors, and 5,000 photographs. Prints and drawings range from the 15th century to the present, and photographs span the history of the medium. Particular strengths are in early modernism, including German Expressionism, and American works of the 19th and early 20th centuries. The Gallery has extraordinary prints by Albrecht Dürer and Rembrandt van Rijn, and a broad range of Italian, French, and Netherlandish drawings. Since the 1970s, the Gallery has been actively acquiring photographs, and the collection includes significant groups of works by Eugène Atget, Berenice Abbott, Walker Evans, and Robert Adams.
The study room also hosts visitors seeking to view works on paper across other curatorial disciplines, including Asian art.